INHIBITION OF EZH2 ALLEVIATES SAHA-INDUCED SENESCENCE-ASSOCIATED SECRETION PHENOTYPE IN SMALL CELL LUNG CANCER CELLS

Inhibition of EZH2 alleviates SAHA-induced senescence-associated secretion phenotype in small cell lung cancer cells

Abstract Chemotherapy has been widely used in small cell lung cancer (SCLC) treatment in the past decades.However, SCLC is easy to recur after chemotherapy.The senescence of cancer cells during chemotherapy is one of the effective therapeutic strategies to inhibit the progression of Heart / Cardiovascular Support cancer.Nevertheless, the senescence

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Application of near-infrared spectroscopy technology in the complex fermentation system to achieve high-efficiency production

Abstract The fermentation process is dynamically changing, and CENTAURY the metabolic status can be grasped through real-time monitoring of environmental parameters.In this study, a real-time and on-line monitoring experiment platform for substrates and products detection was developed based on non-contact type near-infrared (NIR) spectroscopy tech

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Fasciola hepatica is refractory to complement killing by preventing attachment of mannose binding lectin (MBL) and inhibiting MBL-associated serine proteases (MASPs) with serpins.

The complement system is a first-line innate host immune defence against invading pathogens.It is activated via three pathways, termed Classical, Lectin and Alternative, which are mediated by antibodies, carbohydrate arrays or microbial liposaccharides, respectively.The three complement pathways HALVA ALMOND converge in the formation of C3-converta

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